Joseph Benedikt Kleiser was born in Freiburg in Baden, Germany, in 1823. He was baptised there on 19 March 1823. His parents were Jacob Kleiser and Fransizka Geschwander. He had an older brother, Andreas (later Andrew), born in 1819.
On 12 March 1840, Joseph arrived in London via Calais and Belfast. Andrew (under the name Andreas) had arrived two years previously, on 2 Nov 1839.

By the time of the 1841 census, both brothers were working as clockmakers. Joseph lived and worked in Chelmsford, Essex, while Andrew had settled in York, where he lived on Stonegate along with his business partner, Philip Schwerer.

In 1854, Joseph married Mary Potter in York. They had three sons:
Cuthbert Joseph Kleiser (born 1855)
John Henry Kleiser (born 1857)
Louis Augustine Kleiser (born 1860).

Andrew Kleiser had also married into the Potter family. He married Hannah Potter in September 1847 at the Catholic chapel on Little Blake Street. They had one daughter, Jane Frances. She was born in 1849 but died in 1853, aged about four.

Andrew was naturalised in September 1852, and Joseph was naturalised in April 1854.
Andrew died in January 1885, and Joseph later that year in December. As Andrew had no surviving children, the Kleiser business passed to Joseph's three sons, Cuthbert, John, and Louis..

Cuthbert Joseph Kleiser married Hannah Lilian Cundall, the daughter of Luke and Hannah Cundall, in 1888. They had one son, Louis Cyril Kleiser, born 1893. Cuthbert died in 1929.

John Henry Kleiser never married, and died in 1920, a patient at the York Asylum.

Louis Augustine Kleiser also never married, and died in 1943.

Cuthbert's son, Louis Cyril Kleiser, was also known as 'Cyril'. He was born in 1893 and died in 1977.